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 Update: this is why I don’t get my hopes up. Just found out this is another media hype or as I like to call it a hoax. It’s very sad playing with us like this.

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I won’t hold my breath, but please make it so!

Always hoping

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Breakthrough in multiple sclerosis research as scientists discover possible cause of the disease

 Scientists found a protein called Rab32 in the brains of people with MS

Telegraph Reporters

24 April 2017 • 12:01am

British scientists have discovered a potential cause for multiple sclerosis, in a major breakthrough that could pave the way for new treatments for the disease.

Scientists have found a new cellular mechanism which may cause the autoimmune disorder. Multiple sclerosis affects around 2.5 million people around the world.

Typically, people are diagnosed in their 20s and 30s, and it is more common in women than men.

Although the cause has so far been a mystery, the disease causes the body’s own immune system to attack myelin – the fatty “sheaths” which protect nerves in the brain and spinal cord.

This leads to brain damage, a reduction in blood supply and oxygen and the formation of lesions in the body.

Our exciting new findings have uncovered a new avenue for researchers to explore. It is a critical step, and in time, we hope it might lead to effective new treatments for MSProfessor Paul Eggleton

Symptoms can be wide-ranging, and can include muscle spasms, mobility problems, pain, fatigue, and problems with speech.

Scientists have long suspected that mitochondria, the energy-creating “powerhouse” of the cell, plays a link in causing multiple sclerosis.

Using human brain tissue samples, researchers at the Universities of Exeter and Alberta found a protein called Rab32 is present in large quantities in the brains of people with MS – but is virtually absent in healthy brain cells.

Where Rab32 is present, the team discovered that a part of the cell which stores calcium gets too close to the mitochondria.

The resulting miscommunication with the calcium supply triggers the mitochondria to misbehave, ultimately causing toxicity for brain cells in people with MS.

Researchers do not yet know what causes an unwelcome influx of Rab32 but they believe the defect could originate at the base of the celThe finding will enable scientists to search for effective treatments that target Rab32 and embark on determining whether there are other proteins which could pay a role in triggering MS.

Professor Paul Eggleton, of the University of Exeter Medical School, said: “Multiple sclerosis can have a devastating impact on people’s lives, affecting mobility, speech, mental ability and more.

“So far, all medicine can offer is treatment and therapy for the symptoms – as we do not yet know the precise causes, research has been limited.

“Our exciting new findings have uncovered a new avenue for researchers to explore. It is a critical step, and in time, we hope it might lead to effective new treatments for MS.

The research has been published as part of MS Awareness Week. Dr David Schley, from the MS Society, said: “No-one knows for sure why people develop MS and we welcome any research that increases our understanding of how to stop it.

“There are currently no treatments available for many of the more than 100,000 people in the UK who live with this challenging and unpredictable condition.

“We want people with MS to have a range of treatments to choose from, and be able to get the right treatment at the right time.”

Trish Deykin, who suffers from MS, welcomed the research.

She said: “Finding a cause will help everyone who has MS – even if that’s just knowing more about what’s going on in their own brains.”

The paper, Rab32 connects ER stress to mitochondrial defects in multiple sclerosis, is published in the journal Neuroinflammation.

1 year 6 months! SERIOUSLY!!

Bernie Marcus, the founder of HD, was friends with my dad back in the day. Good friends. Doubtful if he’d accept this treatment of customers. Sadly he’s retired now… but you never know.

 The waiting is the hardest part dealing with the Home Depot. I was given two offers last week, one of which would void the warranty, and one which was a complete joke. I didn’t pay for a  separate warranty, the warranty came with the windows. I told them (Briana and Mark) no on both offers and that I would call corporate. Mark Nord was actually on the phone call, The guy who blew me off some months ago then sent me to someone else.  On the phone call every time I tried to speak, they cut me off. Typical of the Home Depot.

 So I got lucky and got through to corporate. The gentleman I spoke with, Michael, said he would do his best to help me. That was Friday.  So, we shall see if he  honestly will help me. Doubtful.. Talked to a Jasmine at corporate a few days before, and she never called back or returned my calls. I really just want and need this over with. I literally cannot sleep with all the crap that goes through my head regarding this.

 I’m really afraid I’m going to have to go and pursue other means. Attorneys, the news, a website where people can share their awful experiences. I really hope I don’t have to go that route.

 And the saga continues…

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Please remember to take care of our planet! She truly is the only one we have. We can fix what we’ve broken.

So let’s all make a pledge to take better care of Mother Earth!

Peace out

 

Have a great weekend all!!

OMG! Baby kitty and a Pibble!

Peace out… for now 😉

Use coupon code funnygirl and receive 40% off anything in my shop. S/H will be 48hrs as I need help with it now.

#sale #shop #jewelry #OOAK

click the pic…

So perfect, so me!!

Bahahahaha!

Peace out! ❤

From: In Defense of Animals

Zoos and aquariums are run by heartless thugs who separate animals from their friends and families for whatever whims they choose.

Wanting baby bear cubs to increase attendance is not a good enough reason to break a bear’s heart. And no, the San Diego Zoo nor Sea World has never restocked wild populations of polar bears, so don’t buy the conservation sham being sold here.

This death is on SeaWorld and the San Diego Zoo’s hands and the people who pay admission to support these corporations. RIP Szenja. We’re sorry that these corporations and so many members of the public didn’t care about you.

For the full article, click on the picture of Szenja. R.I.P. sweet one…